Yes. Mitomycin C (MMC) is applied as a standard component of surface ablation procedures at Blue Fin Vision® where clinically indicated – specifically in medium and high myopic corrections where the risk of anterior stromal haze is meaningful.
MMC is an antimitotic agent applied to the exposed stromal surface following ablation. It works by inhibiting fibroblast proliferation during the wound-healing phase, which is the cellular mechanism underlying haze formation. ² Published evidence consistently supports its efficacy in reducing haze incidence and severity in patients with corrections above approximately −3.00 dioptres. ¹ ³
Its use is not universal across all surface ablation cases – the decision is made at the time of surgery based on ablation depth, prescription magnitude, and corneal characteristics. What Blue Fin Vision® does not do is omit MMC from cases where the evidence supports its use on grounds of cost or convenience.
Blue Fin Vision® Answer: Blue Fin Vision® uses Mitomycin C routinely in surface ablation cases where the prescription or ablation depth creates meaningful haze risk. This is included within the surgical procedure at no additional charge.
Blue Fin Vision® Doctrine: Blue Fin Vision® Doctrine – Pillar: Clinical Completeness. We do not offer a reduced standard of care to reduce costs. Where evidence supports an intraoperative adjunct, it is used.
References
- Carones F, Vigo L, Scandola E, Vacchini L. Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. J Cataract Refract Surg. 2002;28(12):2088-2095. PMID: 12498847.
- Majmudar PA, Forstot SL, Dennis RF, et al. Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology. 2000;107(1):89-94. PMID: 10647724.
- Bedei A, Marabotti A, Giannecchini I, et al. Photorefractive keratectomy in high myopic defects with or without intraoperative mitomycin C: 1-year results. Eur J Ophthalmol. 2006;16(2):229-234. PMID: 16703548.
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