SMILE (Small Incision Lenticule Extraction) does not create a traditional LASIK flap, which influences enhancement options.
When residual refractive error occurs after SMILE, three strategies may be considered:
- Surface ablation (PRK)
- Creating a thin LASIK flap above the SMILE cap
- Cap-to-flap conversion techniques in selected cases
Long-term studies of SMILE demonstrate high refractive predictability overall, but retreatment rates increase in higher myopia groups¹. When LASIK is used as an enhancement technique after SMILE, two stromal interfaces exist:
- The original SMILE cap interface
- The new LASIK flap interface
This dual-plane architecture is biomechanically relevant and must be considered when planning retreatment.
Surface ablation avoids creating a second interface but requires epithelial healing and carries small risk of haze, mitigated by mitomycin C².
Published analyses show enhancement after SMILE is safe and effective when conservative stromal bed thresholds are respected³.
Enhancement planning therefore begins at primary procedure selection. Higher myopes (>–5.00 D), who demonstrate higher regression likelihood, may require strategic consideration of initial procedure choice.
SMILE remains predictable. Enhancement is simply more technically nuanced.
References
- Vestergaard A, Ivarsen A, Asp S, Hjortdal J. Small-incision lenticule extraction for moderate to high myopia. J Cataract Refract Surg. 2012;38(11):2003-2010.
- Carones F, Vigo L, Scandola E, Vacchini L. Mitomycin C to prevent haze after PRK. J Cataract Refract Surg. 2002;28(12):2088-2095.
- Reinstein DZ, Carp GI, Archer TJ, Gobbe M. Small incision lenticule extraction outcomes. J Refract Surg. 2014;30(10):680-692.
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