Cystoid macular oedema (CMO) is fluid build-up in the central retina after cataract or lens replacement surgery. Tiny blood vessels around the fovea become leaky, so fluid collects in cyst-like spaces within the retinal layers.¹
Patients may notice blurred or hazy central vision, reduced contrast or a disappointing “dip” in vision several weeks after an apparently smooth operation. Optical coherence tomography (OCT) shows characteristic pockets of fluid in the outer plexiform and inner nuclear layers.²
Many cases are mild and resolve with treatment, but untreated oedema can delay recovery and occasionally limit best-corrected vision.¹ CMO is usually driven by an inflammatory cascade rather than by “rough” surgical technique.
Understanding this mechanism allows us to design drop regimens and OCT follow-up that reduce the risk of clinically significant oedema and detect changes before they harm vision.
References
- Lobo C. Pseudophakic cystoid macular edema. Ophthalmologica. 2012;227(2):61-67.
- Gharbiya M, Grandinetti F, Scavella V, et al. Correlation between OCT measurement and fluorescein angiography in CMO. Invest Ophthalmol Vis Sci. 2007;48(9):3763-3770.
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