Terrien marginal degeneration is a rare, slowly progressive thinning disorder of the peripheral cornea. It typically affects both eyes but can be asymmetric.
Features and symptoms
The condition often begins in early or middle adulthood and may cause significant astigmatism.
- Peripheral corneal thinning with a leading edge of lipid deposits
- Gradual blurred vision from high against-the-rule astigmatism
- Usually minimal redness or pain, though episodes of inflammation may occur
- Risk of perforation in very advanced thinning
Management
Treatment depends on severity of thinning and visual impact.
- Glasses or rigid contact lenses to correct irregular astigmatism
- Lubricants and occasional anti-inflammatory drops for irritation
- Lamellar or patch graft surgery in cases with marked thinning or risk of perforation
- Regular monitoring with topography and pachymetry
