Drusen are tiny yellow deposits that build up between the retina and its underlying support layer. They are a hallmark of age-related macular degeneration but can also occur in other contexts.
Types and significance
The size and number of drusen influence the risk of developing advanced AMD.
- Small hard drusen may appear with normal ageing
- Larger soft drusen and clusters increase AMD risk
- Often discovered at routine eye exams before symptoms arise
- Seen clearly on OCT and colour fundus photography
Monitoring and management
While drusen themselves are not treated directly, they guide risk assessment.
- Regular monitoring for signs of wet AMD or geographic atrophy
- Lifestyle changes and AREDS-style supplements in suitable patients
- Amsler grid self-checks to spot new distortion early
- Prompt reporting of any sudden central blur or distortion
