Fuchs endothelial dystrophy is a progressive disorder of the innermost corneal layer, the endothelium. As endothelial cells fail, fluid builds up in the cornea, causing swelling and blurred vision.
Symptoms and progression
Patients often notice misty or hazy vision on waking that clears during the day, along with glare and haloes around lights. Over time, persistent oedema can lead to painful blisters (bullae) and permanent scarring.
- More common in middle-aged and older adults
- Often affects both eyes but may be asymmetrical
- Family history is common in some cases
Treatment options
Early stages are managed with salt (hypertonic) drops and careful monitoring. Advanced disease may require endothelial keratoplasty, usually coordinated through corneal or general ophthalmology services.
