Stevens-Johnson syndrome (SJS) is a severe mucocutaneous reaction, usually to medications or infections, that can affect the eyes as well as the skin and mouth. Ocular involvement may lead to chronic dry eye, scarring, and vision loss.
Ocular features
In the acute phase, patients may have conjunctival redness, blistering, and membranes on the ocular surface. Long term, scarring of the conjunctiva, eyelids, and cornea can cause persistent discomfort and reduced vision.
- Often associated with systemic symptoms and skin rash
- Can cause eyelid malposition and lash problems
- Requires multidisciplinary care between ophthalmology and other specialties
Management
Treatment focuses on intensive lubrication, managing inflammation, and protecting the ocular surface. Specialist follow-up in general ophthalmology or ocular surface clinics is essential to limit long-term complications.