---
title: Birdshot chorioretinopathy
description: "Birdshot chorioretinopathy is a rare, chronic, bilateral posterior uveitis strongly associated with HLA-A29. It causes characteristic cream-coloured lesions and progressive visual disturbance. ## Clinical features The condition typically presents in middle age. - Floaters, blurred vision, night vision problems, and…"
url: "https://bluefinvision.com/knowledge-base/topics/conditions-diseases/birdshot-chorioretinopathy/"
updated: "2025-12-16"
category: "Conditions & Diseases"
---

# Birdshot chorioretinopathy

Birdshot chorioretinopathy is a rare, chronic, bilateral posterior uveitis strongly associated with HLA-A29. It causes characteristic cream-coloured lesions and progressive visual disturbance.

## Clinical features

The condition typically presents in middle age.

- Floaters, blurred vision, night vision problems, and photopsia
- Multiple oval, hypopigmented choroidal spots radiating from the optic disc
- Retinal vasculitis, macular oedema, and mild vitritis
- Very strong association with HLA-A29 on blood testing

## Treatment

Long-term immunosuppression is often required to control inflammation.

- Systemic steroids initially, followed by steroid-sparing agents such as mycophenolate or cyclosporine
- Biologic therapies in resistant cases
- OCT and electroretinography to monitor macular and global retinal function
- Regular follow-up to balance disease control with medication side effects